BeadArray Methylation Service
Illumina's Methylation profiling is an array-based platform that combines high sample throughput, high multiplexing, and single-site CpG resolution.
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96 samples per plate, 1,505 CpG loci per sample selected from 807 genes:
12 samples per BeadChip, ~27,000 CpG assays per sample, covering more than 14,000 well-annotated genes, includes more than 1,000 cancer-related genes and 200 CpG sites located within CpG islands found in promoter regions of microRNA (miRNA) genes.
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Customers are able to select assays to target CpG loci within genes or regions of interest to meet specific research needs. Illumina's tech support scientists will evaluate customer submissions and work collaboratively with the customer to ensure optimal probe design. Once all of the assays have been evaluated, a list is sent to the customer for final approval before the Oligo Pool for Methylation Assay (OMA) is manufactured. Custom content can be submitted using any of the following formats:
• NCBI's GeneID
• Gene symbol (HUGO & RefSeq)
• RefSeq mRNA accession number with or without version number
• RefSeq mRNA GI number
• Chromosomal region (RefSeq build, chromosome, pair of coordinates)
• Sequence
Custom methylation is available in panels of 96 and 384-1,536 assays per OMA tube. Larger panels can be accommodated with multiple OMA tubes and the appropriate GoldenGate reagents and arrays. Panels for 384-1,536 loci are available in multiples of 96.
(Source: http://www.illumina.com)